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Nat Immunol (2008) 9:50310

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It serves as a powerful tool for investigating hormone regulation, puberty, and fertility pathways

To prevent ROS production from semiquinones, the cytosolic, NRF2-regulated flavoproteins NAD(P)H: quinone oxidoreductases (NQOs) and aldo-keto reductase (AKR) can compete with P450 reductases and convert quinones to a relatively stable hydroquinones (quinols) [35]

Research models show it modulates central signaling pathways associated with pigmentation, appetite regulation, and autonomic response distinct from peripherally-acting peptides